Mesovarian leiomyomas in the rat.

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Mesovarian leiomyomas in the rat.

Prolonged treatment with two chemically distinct beta-stimulants, Salbutamol and Terbutaline, resulted in mesovarian leiomyomas in Sprague-Dawley rats. Development of these tumors induced by Salbutamol was prevented by concurrent administration of the beta-blocker Propranolol. Mesovarian leiomyomas induced by Salbutomol did not show any regression or progression during a 44-week postdosing reco...

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Ossification in uterine leiomyomas

INTRODUCTION It is common for leiomyoma to undergo various secondary changes like hyaline degeneration, cystic change, myxoid degeneration, infection, necrosis, calcification, red degeneration and very rarely ossification. They are said to result from inadequate blood supply resulting in replacement of muscle fibres by hyaline material, collagen, calcium, mucopolysaccharides or a combination of...

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The management of uterine leiomyomas.

OBJECTIVES The aim of this guideline is to provide clinicians with an understanding of the pathophysiology, prevalence, and clinical significance of myomata and the best evidence available on treatment modalities. OPTIONS The areas of clinical practice considered in formulating this guideline were assessment, medical treatments, conservative treatments of myolysis, selective uterine artery oc...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1987

ISSN: 0091-6765,1552-9924

DOI: 10.1289/ehp.8773107